The major objective of the Data Science Core is to build and manage centralized multi-omics database and provide a full set of bioinformatical, computational and statistical support and integrate all the 3 projects. This will include basic and translational science in systems such as clinical biopsies, PDX, PDO and cell line models, and integration of transcriptomics, spatial, genomics, proteomics and functional biology studies.
The Core will facilitate hypothesis testing across projects by integrating datasets from multiple laboratories using various algorithms, including Bayesian network-based models and Modular Analysis of Genomic NET works In Cancer (MAGNETIC).
Illustration of MAGNETIC.
Illustration of spatial -omics.
The Core is staffed by expert faculty and computational scientists from the Bioinformatics and Computational Biology and Biostatistics Departments at MD Anderson and from the Bioengineering and Therapeutic Sciences Department at UCSF.
